Xanthohumol sup plements

Xanthohumol sup plements

David Sparks Ph.D.
David Sparks Ph.D.
Dr. Adrian Gombart, professor of biochemistry and biophysics in the College of Science at Oregon State University, along with his colleagues are researching the benefits that hops and a derivative in hops called xanthohumol, can help fight abdominal obesity, high blood pressure, high blood sugar among some metabolic functions as well as improve cognitive function. The findings, published in Molecular Nutrition and Food Research, are a key advance in understanding how xanthohumol, a compound that contributes to hops’ flavor, and its derivatives work. That is an important step toward improving the lives of the estimated 35% of U.S. adults who suffer from metabolic syndrome. I had a question for Dr. Gombart.

Is it conceivable in your mind that if someone were to consume hops, that they would get digestive benefits, they would get some relief from some of the symptoms that you just described?

It's a good question, David. It's one reason we are looking at these compounds, because they are sold, like you pointed out, they're sold in all kinds of natural food stores or supplement stores and so forth in various forms. I think generally they're not completely in a hundred percent pure. We work with a very pure form. The amount of xanthohumol, we get in these supplements is not going to speak for all supplements that are out there on the market. I'm not familiar with every one of them. But there's definitely interest in developing them as treatments for various conditions like you've described. However, you don't get the doses that we work with. We're working with pretty high doses in these animals. And then an interesting thing is it's well tolerated. These are doses you could reach in humans.

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